The biotechnology company "Revive" resurrects the extinct giant wolf from 12,000 years ago: extracting fossil DNA, with hopes to cultivate mammoths within 3 years.

Colossal Biosciences, a U.S. biotech company, recently announced that it has successfully bred three young wolves with the characteristics of a "dire wolf" that became extinct about 12,500 years ago. This breakthrough was called the world's first "de-extinction" success story by the company. From a scientist's perspective: Is DeSci really the future revolution in academic research? (Background supplement: CZ, V gods shout together!) Bioscience meme coin pulls up a thousandfold, hot money flocks to DeSci decentralized science track) A biotech company called Colossal Biosciences in Dallas, Texas, USA, recently announced that they have successfully bred three young wolves with the characteristics of a "dire wolf" that became extinct about 12,500 years ago. The breakthrough, which the company calls the world's first "de-extinction" success story, marks a milestone in the use of science and technology to reverse species extinction. The three young wolves, named Romulus, Remus and Khaleesi, are currently placed in a secret location under close surveillance and care. The combination of ancient DNA and gene editing Colossal Biosciences notes that the company was able to achieve this feat because it extracted ancient DNA from dire wolf fossils, such as teeth from 13,000 years ago and skulls from 72,000 years ago, and based on this, modified the genome of the living gray wolf, like a recreation of the Jurassic Park. They used a gene-editing technique called CRISPR to introduce about 20 key mutations into the gray wolf's genome, causing these young wolves to exhibit dire wolf characteristics, including larger body size, thick, light-colored fur, and strong jaw structure. It should not be said that this method does not directly clone dire wolves, but genetically modifies the creation of new individuals similar to ancient species, demonstrating the powerful potential of modern biotechnology. Colossal Biosciences' ambitions to breed mammoths within three years go far beyond dire wolves. The company says its long-term goal is to resurrect more extinct species and plans to apply the technology to ecosystem restoration and the protection of endangered species. Next projects include the resurrection of the dodo and the Australian thylacine, and the company expects to produce woolly mammoths, which are more than 4,000 years extinct, by 2028. Ben Lamm, co-founder of the company, emphasizes: "These efforts are not only to bring disappeared species back to life, but also to enhance the adaptive capacity of existing species through genetic technology, such as helping the American red wolf defend against environmental threats." Expert opinion: achievements and controversy But while Colossal Biosciences considers this result a "dire wolf resurrection," the scientific community is divided on its definition. Nic Rawlence, a paleogeneticist at the University of Otago in New Zealand, pointed out that these young wolves are more like gray wolves with dire wolf characteristics than real dire wolf resurrection. He argues that true "deextinction" should involve the direct cloning of the complete genomes of extinct species, rather than relying on genetic modification of existing species. At the same time, some experts have expressed concern about the ecological impact and ethical issues of this technology, arguing that the resurrection of extinct species may disturb the existing ecological balance, and questioning whether resources should be prioritized for the protection of existing endangered species. But in any case, this breakthrough has undoubtedly opened up new possibilities for the scientific community, and also brought challenges worth pondering. Related meme coins skyrocketed It is worth mentioning that after the news was released, related meme coins also appeared on the meme coin nuggets hot land Solana. According to GMGN data, the memecoin $REMUS, which shares the same name as Remus the young wolf, performed the best, with a market cap of $14.8 million at one point. However, at the moment of writing, the price of the coin has fallen back to $0.0041086, and the market value has fallen around $4 million. The movement zone also reminds investors that the meme coin itself is highly volatile and should be cautious. Related stories Bitter Religion: Artificial Intelligence's Jihad Around the Law of Expansion Suite BIO Protocol Founder Announces 3 More DeSci Projects to Interpret the Value of Decentralized Science CZ promises to interact regularly in the community: enjoy a rare quiet time during this time~ "Meibiotech "resurrected" the dire wolf that was extinct for 12,000 years: extracting fossil DNA, which is expected to breed mammoth elephants within 3 years" This article was first published in the dynamic area BlockTempo The most influential blockchain news media.