Gate.io News, May 21st - Jimo Bio has recently announced its latest research achievement. Jimo has successfully extracted a new active ingredient called "ASCⅡ Extract" from the dry stem cells of the musk deer antler, and named it "Sikavira"️. This extract has the characteristics of high activity, low impurities, high purity, and easy absorption. It is expected to play an important role in anti-aging health care, antioxidant skin care, and medical beauty repair.

On May 9, Jimin Medical issued an announcement on the risk warning of stock trading, and the current stem cell drug research and development pipeline of Boao International Hospital mainly includes adipose mesenchymal stem cells (ADSC) for retinitis pigmentosa (RP), adipose mesenchymal stem cells (ADSC) for type 2 diabetes mellitus (T2DM), and adipose mesenchymal stem cells (ADSC) for chronic obstructive pulmonary disease (COPD), but they are all in the preclinical stage and the project is relatively early. The R&D cycle of innovative drugs is long, the links are long, and the risk is high, and it is easy to be affected by long factors such as technology, approval, and policy from development, clinical trials, approval to production, and there are long uncertainties in the subsequent R&D promotion.

Two independent research teams have successfully regenerated brain circuits in mice using neurons grown from rat stem cells. These two studies were published on April 25th in the journal "Cell," providing valuable insights into how brain tissue forms and offering new approaches to restoring brain function lost due to disease and aging.

Recently, the 37th Annual Conference on Neural Information Processing Systems was held in New Orleans, USA, as reported by IT House on December 31. At the meeting, a scientific team proposed that the artificial intelligence model Transformer has a function similar to the NMDA receptor. In addition to this discovery, they also designed new nonlinear functions that allow the Transformer model to simulate the kinetic performance of NMDA receptors. The NMDA receptor is a "smart" channel that promotes the formation of memories and skills. If glutamate is present in the brain, nerve cells become excited, delivering neurotransmitters to NMDA receptors. At the same time, magnesium ions are responsible for the gatekeeping, and when magnesium ions are squeezed out of the NMDA receptors, the neurotransmitter is allowed to enter the next nerve cell. In the hippocampus, the smooth transfer of matter ensures that short-term memory is effectively converted into long-term memory, and magnesium ions are responsible for selectively allowing matter to pass through. In the new study, the scientists found that there is a process similar to the magnesium ion gatekeeping in the NMDA receptor in the Transformer model, and that adjusting the parameters of the Transformer model can enhance the memory capacity of the model. This finding prompted researchers to think about whether it is possible to develop a method to regulate the memory consolidation process of the Transformer model by studying the mechanism of magnesium ion gatekeeping in the NMDA receptor, and make the model have systematic long-term memory and even consciousness.

According to a report by Cailian News Agency on December 25, scientists at the Broad Institute of the Massachusetts Institute of Technology and Harvard University have discovered a new class of antibiotics using AI technologies such as depth learning. These antibiotics kill two different types of resistant bacteria, offering new hope for tackling the global challenge of antibiotic resistance. According to reports, the researchers trained a Depth learning model using a greatly expanded dataset and tested the effects of about 39,000 compounds on Staphylococcus aureus and three types of human cells from the liver, skeletal muscle, and lungs, and then used the test data to train the AI model. By training, the AI model will be able to predict the antimicrobial activity and potential toxicity of compounds to human cells, and the researchers have found compounds that can both kill microbes and minimize adverse effects on the human body.

Researchers at the University of Texas Southwestern Medical Center in the United States have developed a new artificial intelligence (AI) model that analyzes the spatial arrangement of cells in tissue samples, as reported by the Financial Associated Press on December 13. The innovative approach, published Dec. 11 in Nature Communications, accurately predicts outcomes for cancer patients, marking a significant advance in the use of AI for cancer prognosis and personalized treatment strategies.

According to a report by CaiLian News on October 23, IBM in the United States recently launched a brain-like chip "North Pole", which runs image recognition algorithms driven by artificial intelligence 22 times faster than similar commercial chips and 25 times more energy efficient. The research paper was published in the October 19 issue of Science. The Arctic chip interweaves its computing modules with those that store information, allowing each computing core to access remote blocks as easily as adjacent ones, greatly speeding up the exchange of information between computing units and memory cells. This design idea was inspired by the way the human brain works. IBM had previously built chips called True North based on this idea, but Arctic transformed the technology into a digital architecture compatible with silicon wafer technology used in contemporary computers. Darmendra Modhar of IBM Research Labs, head of the research team, says it's a new way of looking at computer architecture.

According to a report by Science and Technology Innovation Board on September 19, the U.S. Department of Defense and Google have cooperated to develop a new microscope with AI functions that can help doctors detect the presence of cancer cells in patients earlier. American doctor Nadeem Zafar said in an interview that the new product is called Virtual Reality Microscope (ARM). The technology is still in its early stages and has not yet been actively used in diagnosis and treatment, but the initial research and development is progressing well. Zafar said that 13 ARMs have been produced so far and are in the testing phase at the Miter Institute in Washington, the capital. Officials say it could be a useful tool for pathologists. According to estimates, each ARM may cost US$90,000 to US$100,000.

According to a report by Xinhua News Agency on September 5, the Technion-Israel Institute of Technology recently issued a communiqué stating that its researchers have developed an innovative method that combines biology, chemistry and artificial intelligence tools to treat cancer. Related papers were published in the international journal "Journal of Controlled Release". According to the communique, this therapy is based on the concept of "meta-synergy", which means that with the help of efficient artificial intelligence tools, different drugs work together to form nanoparticles through a self-assembly chemical process, achieving a more significant therapeutic effect than a single drug. The nanomedicine produced by this tool can effectively implement targeted therapy on cancer cells, and is more successful in fighting cancer, with less toxicity and fewer side effects.

According to PANews news on August 14, Reuters reporter Luc Cohen tweeted that Bureau of Prison records showed that former FTX CEO Sam Bankman-Fried (SBF) is currently being held at the Metropolitan Detention Center in Sunset Park. Ordering SBF to be jailed a day earlier, Judge Lewis Kaplan admitted that the prison "doesn't belong on anyone's list of five-star facilities". It is reported that the Brooklyn Metropolitan Detention Center is located in New York City, USA, and currently houses more than 1,600 prisoners. The detention center is controversial due to poor supervision conditions and medical and health issues. Decrypt reported that most of the prison's cells lacked individual cells or toilets, and the cells were infested with rats, maggots and insects. Prior to the news on August 12, a U.S. judge revoked SBF's bail; SBF's legal team has appealed against it.