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Pfizer Inc (PFE) Announces Positive Results from BREAKWATER Trial
Pfizer Inc. announced positive results from its BREAKWATER trial for BRAFTOVI in combination with cetuximab and FOLFIRI for metastatic colorectal cancer, showing significant improvement in progression-free survival and overall survival. Despite the positive trial results, some analysts have recently downgraded Pfizer, citing R&D investment risks, even as the company surpassed Q4 2025 earnings estimates. Pfizer plans to submit the detailed results to the FDA for regulatory consideration.