JPMorgan Report Warns on Global Risk Assets, Cuts S&P 500 2026 Target to 7200, Points Out Market Overly Optimistic on Iran Conflict De-escalation. Oil Prices Break Through $110, Suppressing Consumption and Earnings, with Expected Economic Growth Slowdown. If Oil Prices Remain Elevated, S&P 500 Faces 10%-15% Pullback Risk, and Market Volatility May Persist at High Levels.

According to Gate News, a Rune-associated address, co-founder of MakerDAO, recently opened a short position on the S&P 500 index, with positions increasing to $4.66 million. Meanwhile, the address holds $13.6 million in crude oil long positions and $6.1 million in U.S. stocks short positions, totaling over $20 million, possibly betting on economic stagflation.

Biopharmaceutical company Acurx Pharmaceuticals has approved a $10 million Bitcoin purchasing plan to hedge against R&D funding depreciation risks; Enfusion plans to invest 10% of excess cash into Bitcoin and Ethereum; Nature's Miracle launched a $5 million Bitcoin reserve plan, demonstrating that cryptocurrencies are being incorporated into reserve assets. Meanwhile, crypto custody service demand has grown by 40%.

American investment bank Raymond James raised its price target for Nvidia stock to $323, believing the company will achieve $12 billion in sales, demonstrating strong demand and growth prospects. Nvidia's revenue for this quarter is expected to grow 78%, with a forward price-to-earnings ratio lower than the S&P 500 index.

Hyperliquid partners with TradeXYZ to launch the first on-chain S&P 500 perpetual futures contract, authorized by S&P Dow Jones, supporting 24/7 trading and driving traditional financial products into the crypto market. HYPE token surges nearly 2%, up 76% year-to-date, while Hyperliquid leads trading volume in the commodities market.

Gate News reported that on March 19, at the U.S. stock market opening, the Dow Jones Industrial Average fell 0.55%, the S&P 500 Index declined 0.82%, and the Nasdaq Index dropped 1.35%. Precious metals stocks experienced significant declines, with Coeur d'Alene Mines Corporation (CDE.N) down 8%, Newmont Corporation (NEM.N) down 9%, and Pan American Silver Corp (PAAS.O) down 6%. The Nasdaq China Dragon Index fell 1.9%.

On March 19, hawkish comments from the Federal Reserve triggered a decline in U.S. stocks, with the Dow Jones falling 0.64%, the S&P 500 down 0.79%, and the Nasdaq down 1.14%. Crypto-related stocks also declined across the board, with declines seen in Circle, CEX, Riot, and others.

As the trend of tokenizing real-world assets accelerates, the S&P 500 Index has officially entered the crypto derivatives market. Trade XYZ has launched S&P 500 perpetual futures on the Hyperliquid platform, supporting 24/7 trading. This initiative brings institutional index standards into the digital asset ecosystem, meeting user demand and reflecting the accelerating convergence of Wall Street and blockchain. Trading volume on the Hyperliquid platform is rising, with users able to take positions on multiple assets. Analysts believe that traditional financial trading models are undergoing structural changes.

Gate News reports that on March 19, Trade.xyz has deployed the S&P500/USDC (S&P 500, US stock market benchmark index) trading pair on the Hyperliquid platform through the HIP-3 protocol, supporting up to 50x leverage. The contract officially launched last night (March 18), and as of press time, cumulative trading volume has reached $31.5 million, with open interest rapidly climbing to $19.6 million.

Gate News reports that on March 19, Sky co-founder Rune Christensen conducted trading operations on the HyperliquidX platform, using 20x leverage to short the S&P 500 Index (the benchmark index of the US stock market). At the same time, Rune increased the size of his long position in Brent crude oil (the international benchmark for crude oil prices), currently using 7x leverage. Additionally, TWAP orders are running to further increase the position.